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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dc5167dce978ca5f3cb65d43a3cfcbc4b92cd60f9252b063bd3917e12681d9a' 
  AND token = 'Ye/EVPLNcYNptXUm3+ofCP9VyIENZi7mHH9j7ZYGgNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}