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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735cd0c1cb60583929284efb608ffc7f90992f8e1cff5f94524f6b08b9146819' 
  AND token = '+Udpv1GdSGoMRjKWWD1TXip8vVn1jEHI7wfdLceWAZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}