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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c4387872a92229a2a3d57b4e241d84a7231f8f22352c9147532710e0a103a5a' 
  AND token = '7PuxS5yHRWvQw19/t6bkKg/DCAgVFRRcACJrQ/3HMW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}