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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c068129cf151d28325410a011a3df759e880a9d6e8e78bdea0a5acce7692c66' 
  AND token = 'D0REsnTmpq29iGOa78D7RAcP20o0EcNj+wvhfIzZRs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}