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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53ad8dc4b041f1f08e7f09b79d49cfdafd7bc4b7301ac3605baf0c64bfca1ab' 
  AND token = '8V+2vuOaJs2gYydRQubHiFHNfnR0kOgp5QA5vIO2SuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}