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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '708588c7848b43b171bd65ca2e9b7cfbba606b9832831d49ef19879b5a773e90' 
  AND token = 'JU+TAFIZu7A7HhPXAegrJVoBXDlA3xzmQA+gmUEQB2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}