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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0381c449785c0962ad868351ec595a6cba16b9e8e949add27dc4d04a346824eb' 
  AND token = 'OY4N29Yl0tHgFs6iupl9BcsIUIlWCqJUb1w3SvWP6XQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}