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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2253b836893d7a053159401fdb4cda4916e12ebc4097b438bafa531a72002f2' 
  AND token = 'eXtg0v1E5lbYiquTa3KdXp1LSquZmr4AkpLHdQtSTSU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}