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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6b2156698b71dbe185181b3159ba3c0e24d4d2af8b0cfb8b934a29a4d5a3acf' 
  AND token = 'nza+pn3V/cM9dAQjnb4t0Guh0KSP+geCIHaRamk7Drk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}