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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65546e56a3646aa63ed00f0c00f1c122e99ff5affc826a47d56beeea52dc8dbd' 
  AND token = 'dWn6v0BaO17Ix8UiYns+TroamTZXNQ/qNL9Qt78b7VQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}