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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e36165d193aebec116e4e268ab849db713e39769bef79edc37b96d2f09a2a3d' 
  AND token = '/u/uG1QYr7lIuXXEYHcOm+Q3tMYZvwGMlSKtPb6UiUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}