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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43a5adbca0dd7df54786b985052a22a301be088b0e6cf9b9e89b22977e69224b' 
  AND token = '9m4vnT6Aa3vkrC2WEtWnUBx3OzfC7ecJK4v73NHbzdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}