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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10cc4189ee8e95bd6dc547e82f37a3fbfa80a35bfc975d31981085da3e63003b' 
  AND token = 'TBnOtXisEc99B3RfnLj1wjgTjK7fXYCeNF3XA/8QR4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}