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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa57eb7512490e4728bcc2d1124f93369983d499225df6e5bee9afbd13243981' 
  AND token = 'mlDj4xwsaOKcUK7Jgtq3yGbhIrwC1GzDo23Ile+p5yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}