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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad94300e02a351106e48e36349e88ae9ff23c6c3ed718473119fcb2561f00e75' 
  AND token = 'qUC0/Ss2VrJk5afmBRIredqsExcjosPGBBv4POrxiuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}