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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3459b42c616db57f4aca1235af7dab648d621bd84a73de29ac49ad1eef3736f5' 
  AND token = 'i1NljxYB5afC/DVDwTU2gnV4PsoncC+z76+C4MXlQis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}