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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bdd0e36ccff71d26b16fb91ee8d47a65795bcbd4dec23531ea19b5a6453095a' 
  AND token = 'u/rp2yAWBbonBTtehZ0Hxc+znNs/ZyVNSyMxMN66baI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}