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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a742622b9d861f34e3b6f4ca4ad13e4ec282dce396e83315b25521b264b7ba2' 
  AND token = 'CSFPVHqOhiY1RKcrmR8Vdesx775bLRqTp3fnN4cTT24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}