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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab3d8dc32808f9f6dd7f5b09ade547035777ac24cb8368ea502d33aad2bfa431' 
  AND token = 'NrBCPcPkkGMaSRCR2IfuRNakxj8+01yug1n/c5BkYtM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}