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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e465c5f397e3f03f0867641a348fd0e8064631f23b86ee9aee67bee55062bb8' 
  AND token = 'NS1BDqH+bLPyd77fW2M4iWudHDIG32lZKvP6gveZvH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}