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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d0d59542beac8c4c187226d155ee6636b396c453e43be60c90d0929c30090e' 
  AND token = 'qEu42EkfMD0eE5xpC8sSO32Hk4gdJz2B7mlxev+qgJA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}