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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0858f248f0e149d53297568340e1033cc7f87e6450fa976991f4a2cf86d1ebe' 
  AND token = 'DvNo3u20WPwxNAeMI/63G2AykQ2mNJkypxkAM1sp74k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}