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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e114190f45f6861b4bc5010e60d5b74400f8ab44f943c1d0256eacf87513061' 
  AND token = '2A7Td/jRqod8y5MHQrzxEHjn7sWd+GYyPGy/0H5Ulm4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}