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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e36ebd62fd62489ccee2cfb282a962539f797c015f28dce373d07fc07c5fa2c' 
  AND token = 'KwvqGdM3etw7Ml7TKAtSRYq+SD7WZE1f4wPki0cvvps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}