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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52687735a580c18c9b04e0d3a321d7497cf505b1d4e33e39bc63f0442617de43' 
  AND token = 'Bk5qdZgHf/R/lhMeFuAgSQscmhRt6o4mQ9Vn60JokzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}