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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed61066898b2ff1fb4d0749d7a82af18300a7cf9b8c111765f4e82eac44e756' 
  AND token = 'r0oBFQ2rcTdkduVp+t7KtAP0AbUdQ7VI3ZXtqnvZodg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}