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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e922650a581ccbf4b2245b4ded2002b9db22e6ec1a25d9ba7c81f938cf0f79c' 
  AND token = 'w7HXex9a+NhlbxxCD2GfHLhRyIwdaZxBjfKzXHUqC+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}