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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37d488a7b988703c4bd23d0d07342b6a1b97ff8f590f0456d61e3fa05f3ce026' 
  AND token = 'cAyW6/y2jw0goELXaoageL4Yj/tEhIvnohvoKpwOyrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}