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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad29aa2d2cd3769ca0240184f6637968f6e98b0c49490ac9340da6006be4cfd3' 
  AND token = 'EKu7+PgnbadTRAPRlQ/ORLbIsf7Zy0pgzar368FdvgQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}