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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64149afb952350b69881c87065e7eda60e1f668d6e4b3253aad91df1eaa658c8' 
  AND token = 'dnMvIahhPBPV9+lUmyuu34Wp0JWXTW5yvgeRrVR0CZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}