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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2211fa9da4236c3338adf22cb073edc0f920d13d3143b90702d11891402fe79' 
  AND token = 'VlGll++hs75yU6GoB/zuK5SFJ5nyHkBxA2gdiRaPP+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}