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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22cab2f32f84e29446f15eb2d9679cebf5c8fc85b432730e49e68bd43be689c' 
  AND token = 'aAGff0W7MfHptrgbgBCAP1NVFR7AI0Zgx4bToNJ4LWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}