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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324db82740c902b19d53194303676f7c7d17ff2d461d382820b902d71c040781' 
  AND token = 'F7lQ6SQUHVZlrxiPV+l0QD31nmCs2D7r2zn4EIYxTR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}