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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1392d0450132f7e47e7210fec8333948617b851d1c003a2ce9623302122b88f' 
  AND token = '1AD+AVUF6z5r3BXXFJLTSP/wTqTv0qGCShrZDzF176A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}