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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f8b3dcd29070a625490c81547c9964179724826d0ab5180e77bf214b9d40a5c' 
  AND token = '3yNwanSxHR8zGO1wS36H159y/jOoH5MxQebGyvrna/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}