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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b61b65300ebf033128d3dc2269f7abb906e341a8d5560d47aa795654d29c91b' 
  AND token = 'PSEK30z1R5BctUD1dClp+9kVPlW77m/FYovgupWm3iA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}