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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10090b7669793061ceeaef516e35fd01ac9c74b9a182590b7f8712d39afe82a9' 
  AND token = 'bO5WyjTG/rQaOilAHkGcjz2DfxeCYKZ6wGHxdPb8vwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}