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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b933cdeb3533ff7d3d7372d6def97194285b270e27ba67f42addf8536ccf5caf' 
  AND token = 'S0/iipxnMx7E0BgJ7KJ513RTkOsBgm3ngbb1cfsCQQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}