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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '197152b278b08aad33aa7839a4bd26d779ee8808b327ed8565e364316aaabce5' 
  AND token = 'Il1kqM+6oYSj31/ipwXvJmLlCwa5VoYCMUfiMFO7Ml8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}