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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ea46ccc03e6934c90f4e9c3a197be2d994ebabf1627cb7d0e5f037797830cec' 
  AND token = 'w+sURwBg8EfbmMa7O25O7KE3JeejMM7ZnrzOX6fGcC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}