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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c6089e09513fed1db52fed93c670bc744e1c26080eb97f021ded2d4703535f7' 
  AND token = 'x/wPkKVjQ4v8S53dAxgaLfEa8/WylftgC1PGSxY2eH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}