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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4244cead920859738776d372afa2d07ebd37fb19d71b702f212548c6f22f3deb' 
  AND token = 'E4Nu5+Iq8gr+janeG24CDetOeBwVclFKdRZF3EEkSN8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}