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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43e14a4b292883715350f53d9265d97b07038a41371103a3d642fd39bc61f834' 
  AND token = 'vVjfLX/HUON0WWvOAKgya/1lRkzy+EzK/+6W1l/IkEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}