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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65895c1fa27c12c6b1701ef8c44871b236f86babd069e9bda8381b8e5d5f576d' 
  AND token = 'vWIV/grIODGxL4iCyQeGTi6np/+ANNcW8s36BeVIAp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}