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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49f562e7af08f564d8fa247756afaf8bbf2282ef060ca3d52a4671e180712d61' 
  AND token = '8pRHoHekwqK9iIwa4x6ZXIz+VKeGl4PvEnFRC1pNLIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}