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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6d7e3507a7c44749d36c45555c13fdc5adf29ab8a88de329c33b66a0a1e49ca' 
  AND token = 'tW0a/z8u5K9uK75Me5Jvxg9n8DdXHZY31369f0lZTuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}