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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e42e2b5ed18f2380b1ca6b0b58c6746e3e427622dab2d8f8227afcbf9d7b5fb6' 
  AND token = 'xW5qDu30mRyOa8jxtN9/73MPJRFFLvFokSoCDLrZS0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}