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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ea657e48f72c737c8c666a21dfcefb828daa96a6deb75efaa827803a4c6896' 
  AND token = 'SmWLyC8NsyP1gcox9aCRuA12ekzRsYApV+RBgVEC8lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}