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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e443659f6ccea17f32f6533f7546239c9518ff26db0977b75e6fde5768bef70' 
  AND token = '5Vq10j/LHU/wQHe/Cnkt8KZzReiOM18JII1OUv1MthE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}