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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c21748c6be4195342668fb53ab8265d4fb9e4ab7d16802830804108d4850611' 
  AND token = 'tI4tU8/0imAU/R8OuUHgqA+X0/b/QGLpcCON9Zzw0oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}